Fisiopatologia del dengue pan american health organization. It is widespread across asia, the pacific, central and southern america and africa where these mosquitoes exist. Background information word origin may be derived from swahili or spanish 3 forms of dengue. Genotypespecific neutralization and protection by antibodies against dengue vir type 3. Health experts have known about dengue fever for more than 200 years. Jan 20, 20 dengue virus infection has become a global threat affecting around 100 countries in the world. Dengue is a systemic infectious disease of viral etiology, trans.
If you continue browsing the site, you agree to the use of cookies on this website. Platelet transfusions do not decrease the risk of severe bleeding and may instead lead to fluid overload and. These viruses are related to the viruses that cause. They are not indicated and can increase the risk of gi bleeding, hyperglycemia, and immunosuppression. Fever, arthralgia, headache, petechial spots, rash and haemorrhagic manifestations. The disease is caused by four serologically and genetically distinct viruses termed dengue virus denv 1, 2, 3 and 4. Reported incidence of dengue has increased worldwide in recent decades, but little is known about its incidence in africa. There are four serotypes of dengue virus denv 14 that manifest with. Dengue fever frequently asked questions faq for early child. Other niaidfunded investigators are working to develop dengue vaccines using different live. X dont give platelet transfusions for a low platelet count. Dengue fever frequently asked questions faq for early.
These mosquitoes acquire the virus while feeding on the blood of an infected person. Treatment for dengue and dengue hemorrhagic fever is supportive. This enveloped virus contains a positive singlestranded rna genome. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. The vaccine is only recommended in those who have previously had dengue fever or populations in which most people have been previously infected. Dengue hemorrhagic fever is characterized by high fever, bleeding and liver enlargement. The mosquito becomes infected when it bites a person who has dengue virus in their blood. The value of the vaccine is limited by the fact that it may increase the. What is dengue and how can you keep from getting it. Guidelines on the prevention and control of dengue and dengue hemorrhagic fever in the americas. Denv is a member of flaviviridae family and is transmitted to humans by infected female aedes genus, especially aedes aegypti or aedes albopictus.
Dengue management dos and donts x dont use corticosteroids. Management of dengue fever and dengue hemorrhagic fever slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Dengue fever df, dengue haemorrhagic fever dhf, and dengue shock syndrome dss arboviral infection transmitted by the aedes aegypti mosquito originates in african forests independent of humans breeds in water storage containers. Each denv has four or more genetic groups or genotypes. Dengue hemorrhagic fever dhf and dengue shock syndrome dss are the severe andor fatal clinical manifestations of dengue fever. Symptoms typically begin three to fourteen days after infection. Dengue viruses spread to humans by the bite of female mosquitoes. It takes a week or more for the dengue virus to replicate in the mosquito. Mosquitos are a disease carrying vectors that could infect the public such as dengue, malaria, chikungunyam filariasis and japanese encephalitis. Dengue is a viral disease transmitted by some types of mosquitoes.
This enveloped virus contains a positive singlestranded rna gen. Recovery of dengue4 viruses from mosquito vectors and patients during an epidemic of dengue hemorrhagic fever. Mar 12, 2020 dengue is an infection caused by a virus. Aug 17, 2011 management of dengue fever and dengue hemorrhagic fever slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The vaccine approach that is currently been evaluated at niaid for efficacy against dengue animal models and human trials is a weakened recombinant version liveattenuated of the dengue virus. Introduction in the city of balikpapan, dengue hemorrhagic fever dhf is the leading cause of hospital admission for ages below 5 years of age and the fifth most common cause of death. Dengue vaccine is a vaccine used to prevent dengue fever in humans. Dengue fever 3 associated problems dengue can occasionally affect several other body systems,15 either in isolation or along with the classic dengue symptoms. The presence of disease and high prevalence of antibody to. Extra information the ministry of health would like to remind the public to be vigilant towards vector borne diseases especially during the rainy season.
The incidence of dengue has jumped sharply in recent decades as the disease has spread into new geographic regions. Dengue fever frequently asked questions faq for early child care providers 11 march 2016 general questions about dengue fever 1. People get dengue from the bite of an infected mosquito. Comparison of dengue2 and dengue3 virus strains by neutralization tests and identification of a subtype of dengue3. Download fulltext pdf download fulltext pdf dengue virus. In a small proportion of cases, the disease develops into severe dengue, also known as dengue.
Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. Dengue is among the most important mosquitoborne viral disease in the world. Dengue is a disease caused by infection with one of the four dengue virus serotypes denv1, 2, 3, and 4. Dengue encephalitis sir, dengue fever has variable clinical spectrum ranging from asymptomatic infection to lifethreatening dengue haemorrhagic fever and dengue shock syndrome. Natural strain variation and antibody neutralization of dengue serotype3 viruses. This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Soares, jose luis, health program, editora scipione, 2nd edition, 1994. Currently, there is no licensed antiviral agent available against dengue. Management of dengue fever dengue hemorrhagic fever. Dengue fiebre hemorragica del dengue english version. In the tropics and subtropics, it is a leading cause of illness and death. How can you keep yourself or children you care for from getting it. Symptoms include a high fever, headaches, joint and muscle pain, vomiting, and a rash.
Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. It requires urgent hospitalization as it may even lead to death. Dengue fever and dengue hemorrhagic fever are viral diseases transmitted by aedes mosquitoes, usually aedes aegypti. Dengue is the most common vectorborne viral disease in the world, causing an estimated 50 to 100 million infections globally each year and 25,000 deaths. Dengue outbreaks occur each year in north queensland following cases imported from overseas. Soroepidemiologica retrospective analysis of dengue virus. Dengue fever is a virus transmitted to humans through bites from the aedes mosquito, a daybiting mosquito. Studies on dengue and dengue haemorrhagic feverdhf in. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus. During 19602010, a total of 22 countries in africa reported sporadic cases or outbreaks of dengue. Fever, arthralgia, headache, petechial spots, rash and haemorrhagic manifestations are common features. Dengue fever is a virus transmitted by the bite of infected aedes aegypti mosquitoes. Niaid researchers are actively engaged in the search for an effective vaccine against dengue fever.
In the last 50 years, dengue incidence has increased 30fold, worldwide. Dengue is a disease caused by any one of four closely related dengue viruses denv1, denv2, denv3, and denv4. Dengue pronounced dengee fever is a painful, debilitating mosquitoborne disease caused by any one of four closely related dengue viruses. Dengue virus denv infection is the wildest mosquitoborne infection affecting 2.